CD109 Chromosome 6
CD109 molecule
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What This Gene Does
This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Info
Gene Group
"CD molecules|C3 and PZP like, alpha-2-macroglobulin domain containing|Human platelet antigens"
Locus Type
gene with protein product
Location
6q13
Ensembl
ENSG00000156535
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS143676607 | Health Risk | Conflicting classifications of pathogenicity | — |