CADM3 Chromosome 1
Cell adhesion molecule 3
Upload your DNA to see your personal genotypes for variants in CADM3.
What This Gene Does
The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene. [provided by RefSeq, Oct 2016]
Gene Info
Gene Group
"V-set domain containing|C2-set domain containing|Nectins and nectin-like molecules"
Locus Type
gene with protein product
Location
1q23.2
Ensembl
ENSG00000162706
Associated Conditions (4)
Inborn genetic diseases
Charcot-Marie-Tooth disease
axonal
type 2FF
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS138200155 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS2102125471 | Health Risk | Likely pathogenic | Charcot-Marie-Tooth disease, axonal, type 2FF |