ARHGEF5 Chromosome 7
Rho guanine nucleotide exchange factor 5
Upload your DNA to see your personal genotypes for variants in ARHGEF5.
What This Gene Does
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
Dbl family Rho GEFs
Locus Type
gene with protein product
Location
7q35
Ensembl
ENSG00000050327
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS752820457 | Health Risk | Conflicting classifications of pathogenicity | — |