APCDD1 Chromosome 18

APC down-regulated 1

1 variant 1 Health Risk

Upload your DNA to see your personal genotypes for variants in APCDD1.

What This Gene Does

This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.[provided by RefSeq, Sep 2010]

Associated Conditions (1)

Hypotrichosis 1

Key Variants

RS267606659

Pathogenic

Hypotrichosis 1, Hypotrichosis 1

Health Risk

All Variants (1)

RSID	Category	Clinical Significance	Conditions
RS267606659	Health Risk	Pathogenic	Hypotrichosis 1, Hypotrichosis 1