ZYG11B Chromosome 1
Zyg-11 family member B, cell cycle regulator
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What This Gene Does
Involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and protein quality control for misfolded or incompletely synthesized proteins. Part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"ZYG11 cell cycle regulator family|Armadillo like helical domain containing"
Locus Type
gene with protein product
Location
1p32.3
Ensembl
ENSG00000162378
Associated Conditions (1)
Craniofacial microsomia 1
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1365622597 | Health Risk | Likely pathogenic | Craniofacial microsomia 1, Craniofacial microsomia 1 |