ZPBP Chromosome 7
Zona pellucida binding protein
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What This Gene Does
ZPBP is one of several proteins that are thought to participate in secondary binding between acrosome-reacted sperm and the egg-specific extracellular matrix, the zona pellucida (McLeskey et al., 1998 [PubMed 9378618]).[supplied by OMIM, Aug 2008]
Gene Info
Gene Group
Immunoglobulin like domain containing
Locus Type
gene with protein product
Location
7p12.2
Ensembl
ENSG00000042813
Associated Conditions (1)
Spermatogenic failure 66
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS2128782038 | Health Risk | Pathogenic | Spermatogenic failure 66, Spermatogenic failure 66 |