ZNF418 Chromosome 19

Zinc finger protein 418
1 variant 1 Health Risk

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What This Gene Does
Enables DNA-binding transcription repressor activity. Predicted to be involved in microautophagy; regulation of proteasomal ubiquitin-dependent protein catabolic process; and regulation of transcription by RNA polymerase II. Is active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"Zinc fingers C2H2-type|KRAB domain containing"
Locus Type
gene with protein product
Location
19q13.43
Ensembl
ENSG00000196724
Associated Conditions (1)
Moyamoya angiopathy
Key Variants
All Variants (1)
RSID Category Clinical Significance Conditions
RS2072226563 Health Risk Likely pathogenic Moyamoya angiopathy, Moyamoya angiopathy
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