ZMYND15 Chromosome 17

Zinc finger MYND-type containing 15
6 variants 6 Health Risk

Upload your DNA to see your personal genotypes for variants in ZMYND15.

What This Gene Does
This gene encodes a MYND-containing zinc-binding protein with a nuclear localization sequence. A similar gene in mice has been shown to act as a testis-specific transcriptional repressor by recruiting histone deacetylase enzymes to regulate spatiotemporal expression of many haploid genes. This protein may play an important role in spermatogenesis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]
Gene Info
Gene Group
Zinc fingers MYND-type
Locus Type
gene with protein product
Location
17p13.2
Ensembl
ENSG00000141497
Associated Conditions (3)
ZMYND15-related disorder
Non-obstructive azoospermia
Spermatogenic failure 14
Key Variants
All Variants (6)
RSID Category Clinical Significance Conditions
RS148980412 Health Risk Conflicting classifications of pathogenicity ZMYND15-related disorder, ZMYND15-related disorder
RS148161063 Health Risk Pathogenic Non-obstructive azoospermia, Non-obstructive azoospermia
RS1484755918 Health Risk Pathogenic Spermatogenic failure 14, Spermatogenic failure 14
RS2150630821 Health Risk Pathogenic Spermatogenic failure 14, Spermatogenic failure 14
RS587777432 Health Risk Pathogenic Spermatogenic failure 14, Spermatogenic failure 14
RS752801920 Health Risk Pathogenic Spermatogenic failure 14, Spermatogenic failure 14
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