ZHX3 Chromosome 20
Zinc fingers and homeoboxes 3
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What This Gene Does
This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
"Zinc fingers C2H2-type|ZF class homeoboxes and pseudogenes"
Locus Type
gene with protein product
Location
20q12
Ensembl
ENSG00000174306
Associated Conditions (1)
ZHX3-related disorder
Key Variants
All Variants (3)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS147861291 | Health Risk | Conflicting classifications of pathogenicity | ZHX3-related disorder, ZHX3-related disorder |
| RS368477337 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS915243358 | Health Risk | Conflicting classifications of pathogenicity | — |