XPO5 Chromosome 6
Exportin 5
Upload your DNA to see your personal genotypes for variants in XPO5.
What This Gene Does
This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process. [provided by RefSeq, Aug 2011]
Gene Info
Gene Group
Exportins
Locus Type
gene with protein product
Location
6p21.1
Ensembl
ENSG00000124571
Associated Conditions (1)
XPO5-related disorder
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS111387355 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS200605932 | Health Risk | Conflicting classifications of pathogenicity | XPO5-related disorder, XPO5-related disorder |