WASHC2C Chromosome 10

WASH complex subunit 2C
1 variant 1 Health Risk

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What This Gene Does
Enables phosphatidylinositol phosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and retromer complex binding activity. Involved in several processes, including endosomal transport; negative regulation of barbed-end actin filament capping; and protein localization to endosome. Located in cytosol; early endosome; and nucleolus. Part of WASH complex. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
WASH complex
Locus Type
gene with protein product
Location
10q11.22
Ensembl
ENSG00000172661
Key Variants
All Variants (1)
RSID Category Clinical Significance Conditions
RS374655951 Health Risk Conflicting classifications of pathogenicity
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