USP25 Chromosome 21
Ubiquitin specific peptidase 25
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What This Gene Does
Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 [PubMed 10644437]).[supplied by OMIM, Mar 2008]
Gene Info
Gene Group
Ubiquitin specific peptidases
Locus Type
gene with protein product
Location
21q21.1
Ensembl
ENSG00000155313
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS143875283 | Health Risk | Conflicting classifications of pathogenicity | — |