UGT8 Chromosome 4
UDP glycosyltransferase 8
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What This Gene Does
The protein encoded by this gene belongs to the UDP-glycosyltransferase family. It catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central and peripheral nervous systems. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Info
Gene Group
"UDP glucuronosyltransferases|MicroRNA protein coding host genes"
Locus Type
gene with protein product
Location
4q26
Ensembl
ENSG00000174607
Associated Conditions (1)
Hepatocellular carcinoma
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS149080130 | Health Risk | Conflicting classifications of pathogenicity | Hepatocellular carcinoma, Hepatocellular carcinoma |