TTF2 Chromosome 1
Transcription termination factor 2
Upload your DNA to see your personal genotypes for variants in TTF2.
What This Gene Does
This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
"Zinc fingers GRF-type|SNF2 related family|MicroRNA protein coding host genes"
Locus Type
gene with protein product
Location
1p13.1
Ensembl
ENSG00000116830
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS140571064 | Health Risk | Conflicting classifications of pathogenicity | — |