TSPYL2 Chromosome X
TSPY like 2
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What This Gene Does
This gene encodes a member of the testis-specific protein Y-encoded, TSPY-like/SET/nucleosome assembly protein-1 superfamily. The encoded protein is localized to the nucleolus where it functions in chromatin remodeling and as an inhibitor of cell-cycle progression. This protein may play a role in the suppression of tumor growth. [provided by RefSeq, Sep 2009]
Gene Info
Gene Group
TSPYL family
Locus Type
gene with protein product
Location
Xp11.22
Ensembl
ENSG00000184205
Associated Conditions (3)
Thyroid cancer
nonmedullary
1
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS201527496 | Health Risk | Conflicting classifications of pathogenicity | Thyroid cancer, nonmedullary, 1 |