TNS3 Chromosome 7
Tensin 3
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What This Gene Does
Predicted to enable guanyl-nucleotide exchange factor adaptor activity. Predicted to be involved in positive regulation of Rac protein signal transduction and positive regulation of guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within several processes, including bone resorption; negative regulation of Rho protein signal transduction; and podosome assembly. Located in cytosol and focal adhesion. [provided by Alliance of Genome Resources, Apr 2025]
Gene Info
Gene Group
"SH2 domain containing|C2 tensin-type domain containing"
Locus Type
gene with protein product
Location
7p12.3
Ensembl
ENSG00000136205
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS202060822 | Health Risk | Conflicting classifications of pathogenicity | — |