TMEM87B Chromosome 2

Transmembrane protein 87B
1 variant 1 Health Risk

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What This Gene Does
This gene encodes a protein that may interact with human papillomavirus type 18 E6 oncogene. The protein is also likely to be involved in endosome-to-trans-Golgi network retrograde transport. The gene is expressed in adult and fetal tissues, including brain and heart. This gene is a component of the 2q13 deletion syndrome. Mutations in this gene may be associated with congenital heart defects. [provided by RefSeq, Aug 2016]
Gene Info
Gene Group
7TM uncharacterized proteins
Locus Type
gene with protein product
Location
2q13
Ensembl
ENSG00000153214
Key Variants
All Variants (1)
RSID Category Clinical Significance Conditions
RS369634007 Health Risk Likely pathogenic
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