THOC1 Chromosome 18

THO complex subunit 1
1 variant 1 Health Risk

Upload your DNA to see your personal genotypes for variants in THOC1.

What This Gene Does
Predicted to enable DNA binding activity and RNA binding activity. Involved in mRNA export from nucleus. Located in chromosome, telomeric region; cytoplasm; and nuclear speck. Part of THO complex part of transcription export complex. Implicated in autosomal dominant nonsyndromic deafness 86. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
THO complex
Locus Type
gene with protein product
Location
18p11.32
Ensembl
ENSG00000079134
Associated Conditions (2)
Hearing loss
autosomal dominant 86
Key Variants
RS2509932355
Pathogenic
Hearing loss, autosomal dominant 86, Hearing loss
Health Risk
All Variants (1)
RSID Category Clinical Significance Conditions
RS2509932355 Health Risk Pathogenic Hearing loss, autosomal dominant 86, Hearing loss
Sign Up to Analyze Your DNA Log In