TGM4 Chromosome 3

Transglutaminase 4

1 variant 1 Health Risk

Upload your DNA to see your personal genotypes for variants in TGM4.

What This Gene Does

Predicted to enable protein-glutamine gamma-glutamyltransferase activity. Predicted to act upstream of or within mating plug formation. Located in Golgi apparatus and collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2025]

Gene Info

Gene Group

Transglutaminases

Locus Type

gene with protein product

Location

3p21.31

Ensembl

ENSG00000163810

Associated Conditions (1)

Essential tremor

Key Variants

RS139860990

Likely pathogenic

Essential tremor, Essential tremor

Health Risk

All Variants (1)

RSID	Category	Clinical Significance	Conditions
RS139860990	Health Risk	Likely pathogenic	Essential tremor, Essential tremor