TENM4 Chromosome 11
Teneurin transmembrane protein 4
Upload your DNA to see your personal genotypes for variants in TENM4.
What This Gene Does
The protein encoded by this gene plays a role in establishing proper neuronal connectivity during development. Defects in this gene have been associated with hereditary essential tremor-5. [provided by RefSeq, Oct 2016]
Gene Info
Gene Group
"MicroRNA protein coding host genes|Teneurin transmembrane protein family"
Locus Type
gene with protein product
Location
11q14.1
Ensembl
ENSG00000149256
Associated Conditions (4)
Tremor
hereditary essential
5
TENM4-related disorder
Key Variants
RS141706152
Conflicting classifications of pathogenicity
Health Risk
RS191549326
Conflicting classifications of pathogenicity
Health Risk
RS199687168
Conflicting classifications of pathogenicity
Tremor, hereditary essential, 5
Health Risk
RS199909021
Conflicting classifications of pathogenicity
Health Risk
RS199973967
Conflicting classifications of pathogenicity
TENM4-related disorder, TENM4-related disorder
Health Risk
RS200271895
Conflicting classifications of pathogenicity
TENM4-related disorder, TENM4-related disorder
Health Risk
RS200318543
Conflicting classifications of pathogenicity
TENM4-related disorder, TENM4-related disorder
Health Risk
RS201076845
Conflicting classifications of pathogenicity
Health Risk
RS201191369
Conflicting classifications of pathogenicity
Health Risk
RS201960718
Conflicting classifications of pathogenicity
TENM4-related disorder, TENM4-related disorder
Health Risk
RS201995608
Conflicting classifications of pathogenicity
Tremor, hereditary essential, 5
Health Risk
RS202046911
Conflicting classifications of pathogenicity
Health Risk
All Variants (21)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS141706152 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS191549326 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS199687168 | Health Risk | Conflicting classifications of pathogenicity | Tremor, hereditary essential, 5 |
| RS199909021 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS199973967 | Health Risk | Conflicting classifications of pathogenicity | TENM4-related disorder, TENM4-related disorder |
| RS200271895 | Health Risk | Conflicting classifications of pathogenicity | TENM4-related disorder, TENM4-related disorder |
| RS200318543 | Health Risk | Conflicting classifications of pathogenicity | TENM4-related disorder, TENM4-related disorder |
| RS201076845 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS201191369 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS201960718 | Health Risk | Conflicting classifications of pathogenicity | TENM4-related disorder, TENM4-related disorder |
| RS201995608 | Health Risk | Conflicting classifications of pathogenicity | Tremor, hereditary essential, 5 |
| RS202046911 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS369387606 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS371168354 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS372765091 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS561431723 | Health Risk | Conflicting classifications of pathogenicity | Tremor, hereditary essential, 5 |
| RS76738817 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS772977333 | Health Risk | Conflicting classifications of pathogenicity | TENM4-related disorder, Tremor, hereditary essential |
| RS1555080708 | Health Risk | Likely pathogenic | — |
| RS2136208238 | Health Risk | Pathogenic | Tremor, hereditary essential, 5 |
| RS763485258 | Health Risk | Pathogenic | Tremor, hereditary essential, 5 |