TDRD1 Chromosome 10
Tudor domain containing 1
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What This Gene Does
This gene encodes a protein containing a tudor domain that is thought to function in the suppression of transposable elements during spermatogenesis. The related protein in mouse forms a complex with piRNAs and Piwi proteins to promote methylation and silencing of target sequences. This gene was observed to be upregulated by ETS transcription factor ERG in prostate tumors. [provided by RefSeq, Sep 2018]
Gene Info
Gene Group
"Zinc fingers MYND-type|Tudor domain containing"
Locus Type
gene with protein product
Location
10q25.3
Ensembl
ENSG00000095627
Associated Conditions (1)
Male infertility
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS745783399 | Health Risk | Likely pathogenic | Male infertility, Male infertility |