TAOK2 Chromosome 16
TAO kinase 2
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What This Gene Does
Enables mitogen-activated protein kinase kinase binding activity; neuropilin binding activity; and protein serine/threonine kinase activity. Involved in several processes, including focal adhesion assembly; intracellular signal transduction; and positive regulation of MAPK cascade. Located in cytoplasmic vesicle; cytosol; and nuclear lumen. Part of receptor complex. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
Mitogen-activated protein kinase kinase kinases
Locus Type
gene with protein product
Location
16p11.2
Ensembl
ENSG00000149930
Key Variants
RS373807941
Conflicting classifications of pathogenicity
Health Risk
RS540709989
Conflicting classifications of pathogenicity
Health Risk
RS563881487
Conflicting classifications of pathogenicity
Health Risk
RS760416360
Conflicting classifications of pathogenicity
Health Risk
RS765912677
Conflicting classifications of pathogenicity
Health Risk
RS766814244
Conflicting classifications of pathogenicity
Health Risk
RS774537800
Conflicting classifications of pathogenicity
Health Risk
RS970533552
Conflicting classifications of pathogenicity
Health Risk
All Variants (8)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS373807941 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS540709989 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS563881487 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS760416360 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS765912677 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS766814244 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS774537800 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS970533552 | Health Risk | Conflicting classifications of pathogenicity | — |