SRPRB Chromosome 3
SRP receptor subunit beta
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What This Gene Does
The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
Signal recognition particle GTPases
Locus Type
gene with protein product
Location
3q22.1
Ensembl
ENSG00000144867
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS563903739 | Health Risk | Conflicting classifications of pathogenicity | — |