SRGAP3 Chromosome 3

SLIT-ROBO Rho GTPase activating protein 3
1 variant 1 Health Risk

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What This Gene Does
Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of cell migration and regulation of postsynapse assembly. Is active in postsynapse. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"F-BAR domain containing|AH/BAR family Rho GTPase activating proteins"
Locus Type
gene with protein product
Location
3p25.3
Ensembl
ENSG00000196220
Associated Conditions (1)
Moyamoya angiopathy
Key Variants
All Variants (1)
RSID Category Clinical Significance Conditions
RS1033693138 Health Risk Likely pathogenic Moyamoya angiopathy, Moyamoya angiopathy
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