SPIN4 Chromosome X

Spindlin family member 4

1 variant 1 Health Risk

Upload your DNA to see your personal genotypes for variants in SPIN4.

What This Gene Does

Enables methylated histone binding activity. Involved in negative regulation of cell population proliferation and positive regulation of canonical Wnt signaling pathway. Located in chromatin; cytoplasm; and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

Gene Info

Gene Group

"Tudor domain containing|Spindlin family"

Locus Type

gene with protein product

Location

Xq11.1

Ensembl

ENSG00000186767

Associated Conditions (1)

Lui-Jee-Baron syndrome

Key Variants

RS2519642745

Pathogenic

Lui-Jee-Baron syndrome, Lui-Jee-Baron syndrome

Health Risk

All Variants (1)

RSID	Category	Clinical Significance	Conditions
RS2519642745	Health Risk	Pathogenic	Lui-Jee-Baron syndrome, Lui-Jee-Baron syndrome