SLIT3 Chromosome 5

Slit guidance ligand 3

1 variant 1 Health Risk

Upload your DNA to see your personal genotypes for variants in SLIT3.

What This Gene Does

The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

Gene Info

Gene Group

MicroRNA protein coding host genes

Locus Type

gene with protein product

Location

5q34-q35.1

Ensembl

ENSG00000184347

Associated Conditions (1)

Familial congenital diaphragmatic hernia

Key Variants

RS926590189

Likely pathogenic

Familial congenital diaphragmatic hernia, Familial congenital diaphragmatic hernia

Health Risk

All Variants (1)

RSID	Category	Clinical Significance	Conditions
RS926590189	Health Risk	Likely pathogenic	Familial congenital diaphragmatic hernia, Familial congenital diaphragmatic hernia