SLC9A4 Chromosome 2

Solute carrier family 9 member A4
4 variants 4 Health Risk

Upload your DNA to see your personal genotypes for variants in SLC9A4.

What This Gene Does
Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in monoatomic cation transmembrane transport; regulation of intracellular pH; and transepithelial ammonium transport. Predicted to act upstream of or within gastric acid secretion and glandular epithelial cell development. Predicted to be located in basolateral plasma membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
Solute carrier family 9
Locus Type
gene with protein product
Location
2q12.1
Ensembl
ENSG00000180251
Associated Conditions (1)
Ascending aortic dissection
Key Variants
All Variants (4)
RSID Category Clinical Significance Conditions
RS11692304 Health Risk association Ascending aortic dissection, Ascending aortic dissection
RS1468788 Health Risk association Ascending aortic dissection, Ascending aortic dissection
RS4241211 Health Risk association Ascending aortic dissection, Ascending aortic dissection
RS4851608 Health Risk association Ascending aortic dissection, Ascending aortic dissection
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