SLC26A8 Chromosome 6
Solute carrier family 26 member 8
Upload your DNA to see your personal genotypes for variants in SLC26A8.
What This Gene Does
This gene encodes a member of the SLC26 gene family of anion transporters. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. The expression of this gene appears to be restricted to spermatocytes. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2010]
Gene Info
Gene Group
Solute carrier family 26
Locus Type
gene with protein product
Location
6p21.31
Ensembl
ENSG00000112053
Associated Conditions (1)
Spermatogenic failure 3
Key Variants
RS142724470
Conflicting classifications of pathogenicity
Spermatogenic failure 3, Spermatogenic failure 3
Health Risk
RS368170044
Conflicting classifications of pathogenicity
Health Risk
RS1220970427
Pathogenic
Spermatogenic failure 3, Spermatogenic failure 3
Health Risk
RS140210148
Pathogenic
Spermatogenic failure 3, Spermatogenic failure 3
Health Risk
RS2127298549
Pathogenic
Spermatogenic failure 3, Spermatogenic failure 3
Health Risk
All Variants (5)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS142724470 | Health Risk | Conflicting classifications of pathogenicity | Spermatogenic failure 3, Spermatogenic failure 3 |
| RS368170044 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS1220970427 | Health Risk | Pathogenic | Spermatogenic failure 3, Spermatogenic failure 3 |
| RS140210148 | Health Risk | Pathogenic | Spermatogenic failure 3, Spermatogenic failure 3 |
| RS2127298549 | Health Risk | Pathogenic | Spermatogenic failure 3, Spermatogenic failure 3 |