SLC26A2 Chromosome 5

Solute carrier family 26 member 2
245 variants 245 Health Risk

Upload your DNA to see your personal genotypes for variants in SLC26A2.

What This Gene Does
The diastrophic dysplasia sulfate transporter is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias. It apparently is critical in cartilage for sulfation of proteoglycans and matrix organization. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
Solute carrier family 26
Locus Type
gene with protein product
Location
5q32
Ensembl
ENSG00000155850
Associated Conditions (15)
Atelosteogenesis type II
Multiple epiphyseal dysplasia type 4
Diastrophic dysplasia
Achondrogenesis
type IB
Osteochondrodysplasia
Sulfate transporter-related osteochondrodysplasia
Connective tissue disorder
Inborn genetic diseases
SLC26A2-related disorder
Ovarian serous cystadenocarcinoma
broad bone-platyspondylic variant
3MC syndrome 2
De la Chapelle dysplasia
SLC26A2-related skeletal dysplasia
Key Variants
RS104893917
Conflicting classifications of pathogenicity
Atelosteogenesis type II, Multiple epiphyseal dysplasia type 4, Diastrophic dysplasia
Health Risk
RS114212275
Conflicting classifications of pathogenicity
Sulfate transporter-related osteochondrodysplasia, Atelosteogenesis type II, Multiple epiphyseal dysplasia type 4
Health Risk
RS114569184
Conflicting classifications of pathogenicity
Diastrophic dysplasia, Atelosteogenesis type II, Multiple epiphyseal dysplasia type 4
Health Risk
RS114919633
Conflicting classifications of pathogenicity
Diastrophic dysplasia, Multiple epiphyseal dysplasia type 4, Sulfate transporter-related osteochondrodysplasia
Health Risk
RS115111282
Conflicting classifications of pathogenicity
Achondrogenesis, type IB, Diastrophic dysplasia
Health Risk
RS115383424
Conflicting classifications of pathogenicity
Sulfate transporter-related osteochondrodysplasia, Atelosteogenesis type II, Multiple epiphyseal dysplasia type 4
Health Risk
RS115977282
Conflicting classifications of pathogenicity
Atelosteogenesis type II, Achondrogenesis, type IB
Health Risk
RS116302615
Conflicting classifications of pathogenicity
Achondrogenesis, type IB, Sulfate transporter-related osteochondrodysplasia
Health Risk
RS116443969
Conflicting classifications of pathogenicity
Achondrogenesis, type IB, Diastrophic dysplasia
Health Risk
RS116657359
Conflicting classifications of pathogenicity
Multiple epiphyseal dysplasia type 4, Achondrogenesis, type IB
Health Risk
RS1179580843
Conflicting classifications of pathogenicity
Achondrogenesis, type IB, Atelosteogenesis type II
Health Risk
RS139051143
Conflicting classifications of pathogenicity
Diastrophic dysplasia, Atelosteogenesis type II, Multiple epiphyseal dysplasia type 4
Health Risk
All Variants (245)
RSID Category Clinical Significance Conditions
RS104893921 Health Risk Likely pathogenic Diastrophic dysplasia, broad bone-platyspondylic variant, Osteochondrodysplasia
RS104893924 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Diastrophic dysplasia, Achondrogenesis
RS1057517462 Health Risk Likely pathogenic Achondrogenesis, type IB, Diastrophic dysplasia
RS1057517471 Health Risk Likely pathogenic Atelosteogenesis type II, Achondrogenesis, type IB
RS1057517483 Health Risk Likely pathogenic Achondrogenesis, type IB, Multiple epiphyseal dysplasia type 4
RS1057517496 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Atelosteogenesis type II, Diastrophic dysplasia
RS1057517502 Health Risk Likely pathogenic Atelosteogenesis type II, Achondrogenesis, type IB
RS1057517513 Health Risk Likely pathogenic Atelosteogenesis type II, Diastrophic dysplasia, Achondrogenesis
RS1057517514 Health Risk Likely pathogenic Diastrophic dysplasia, Achondrogenesis, type IB
RS1057517523 Health Risk Likely pathogenic Atelosteogenesis type II, Diastrophic dysplasia, Achondrogenesis
RS1057517526 Health Risk Likely pathogenic Diastrophic dysplasia, Achondrogenesis, type IB
RS1057518327 Health Risk Likely pathogenic
RS114665866 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS1216415565 Health Risk Likely pathogenic
RS1299733113 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS1395122785 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS1464897690 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS1554095084 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Multiple epiphyseal dysplasia type 4
RS1554095097 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Multiple epiphyseal dysplasia type 4
RS1554095125 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Multiple epiphyseal dysplasia type 4
RS1554095137 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Multiple epiphyseal dysplasia type 4
RS1554095145 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Multiple epiphyseal dysplasia type 4
RS1554095156 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Multiple epiphyseal dysplasia type 4
RS1554095167 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Achondrogenesis, type IB
RS1554095266 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Multiple epiphyseal dysplasia type 4
RS1554095356 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Multiple epiphyseal dysplasia type 4
RS1554095381 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Multiple epiphyseal dysplasia type 4
RS1554095395 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Multiple epiphyseal dysplasia type 4
RS1581223549 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS1581232733 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Diastrophic dysplasia, Achondrogenesis
RS1755018723 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS1755079640 Health Risk Likely pathogenic Osteochondrodysplasia, Osteochondrodysplasia
RS1755106202 Health Risk Likely pathogenic Sulfate transporter-related osteochondrodysplasia, Sulfate transporter-related osteochondrodysplasia
RS2113697665 Health Risk Likely pathogenic Diastrophic dysplasia, Diastrophic dysplasia
RS2113698521 Health Risk Likely pathogenic Multiple epiphyseal dysplasia type 4, Achondrogenesis, type IB
RS2113698643 Health Risk Likely pathogenic Diastrophic dysplasia, Diastrophic dysplasia
RS2113698650 Health Risk Likely pathogenic Atelosteogenesis type II, Atelosteogenesis type II
RS2113698845 Health Risk Likely pathogenic Achondrogenesis, type IB, Atelosteogenesis type II
RS2113698870 Health Risk Likely pathogenic Achondrogenesis, type IB, Atelosteogenesis type II
RS2480770174 Health Risk Likely pathogenic
RS2480770240 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS2480770468 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS2480770713 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS2480771535 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS2480771602 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS2480774287 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS2480774496 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS2480775090 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS2480775447 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
RS2480775493 Health Risk Likely pathogenic Achondrogenesis, type IB, Achondrogenesis
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