SDC3 Chromosome 1

Syndecan 3
2 variants 2 Health Risk

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What This Gene Does
The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009]
Gene Info
Gene Group
Syndecans
Locus Type
gene with protein product
Location
1p35.2
Ensembl
ENSG00000162512
Associated Conditions (2)
Obesity
association with
Key Variants
RS2282440
association
Obesity, association with, Obesity
Health Risk
RS2491132
association
Obesity, association with, Obesity
Health Risk
All Variants (2)
RSID Category Clinical Significance Conditions
RS2282440 Health Risk association Obesity, association with, Obesity
RS2491132 Health Risk association Obesity, association with, Obesity
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