RPUSD3 Chromosome 3

RNA pseudouridine synthase D3
2 variants 2 Health Risk

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What This Gene Does
This gene encodes a protein that functions in the assembly of the mitochondrial ribosome by adding a pseudouridine group to 16S rRNA. Loss of this gene results in causes defects in mitochondrial protein production. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2017]
Gene Info
Gene Group
"RNA pseudouridylate synthase domain containing|Pseudouridine synthases"
Locus Type
gene with protein product
Location
3p25.3
Ensembl
ENSG00000156990
Associated Conditions (1)
Inborn genetic diseases
Key Variants
All Variants (2)
RSID Category Clinical Significance Conditions
RS142932960 Health Risk Likely pathogenic Inborn genetic diseases, Inborn genetic diseases
RS767103943 Health Risk Likely pathogenic Inborn genetic diseases, Inborn genetic diseases
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