RNLS Chromosome 10

Renalase, FAD dependent amine oxidase

2 variants 2 Health Risk

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What This Gene Does

Enables several functions, including NADH binding activity; epinephrine binding activity; and monoamine oxidase activity. Involved in negative regulation of blood pressure and negative regulation of heart rate. Located in extracellular region. Implicated in essential hypertension and hypertension. Biomarker of end stage renal disease. [provided by Alliance of Genome Resources, Jul 2025]

Gene Info

Gene Group

Flavoproteins

Locus Type

gene with protein product

Location

10q23.31

Ensembl

ENSG00000184719

Associated Conditions (1)

Family history

Key Variants