RHOB Chromosome 2

Ras homolog family member B

1 variant 1 Health Risk

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What This Gene Does

Predicted to enable GTP binding activity and GTPase activity. Involved in several processes, including cellular response to hydrogen peroxide; cellular response to ionizing radiation; and regulation of cell migration. Located in cleavage furrow and endosome membrane. Biomarker of breast cancer. [provided by Alliance of Genome Resources, Jul 2025]

Gene Info

Gene Group

Rho family GTPases

Locus Type

gene with protein product

Location

2p24.1

Ensembl

ENSG00000143878

Associated Conditions (3)

Recurrent pancreatitis

"See Cases"