PXDNL Chromosome 8

Peroxidasin like
3 variants 3 Health Risk

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What This Gene Does
Predicted to enable heme binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to be located in endoplasmic reticulum; extracellular region; and plasma membrane. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"I-set domain containing|Heme peroxidase family"
Locus Type
gene with protein product
Location
8q11.22-q11.23
Ensembl
ENSG00000147485
Associated Conditions (1)
PXDNL-related disorder
Key Variants
All Variants (3)
RSID Category Clinical Significance Conditions
RS148872370 Health Risk Conflicting classifications of pathogenicity PXDNL-related disorder, PXDNL-related disorder
RS199879389 Health Risk Conflicting classifications of pathogenicity
RS201500226 Health Risk Conflicting classifications of pathogenicity
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