PRAMEF4 Chromosome 1

PRAME family member 4
1 variant 1 Health Risk

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What This Gene Does
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in acrosomal vesicle. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
PRAME family
Locus Type
gene with protein product
Location
1p36.21
Ensembl
ENSG00000243073
Key Variants
All Variants (1)
RSID Category Clinical Significance Conditions
RS138413231 Health Risk Conflicting classifications of pathogenicity
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