PPP1R35 Chromosome 7

Protein phosphatase 1 regulatory subunit 35

1 variant 1 Health Risk

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What This Gene Does

Predicted to enable phosphatase binding activity and protein phosphatase inhibitor activity. Involved in positive regulation of centriole elongation. Located in centriole and centrosome. [provided by Alliance of Genome Resources, Jul 2025]

Gene Info

Gene Group

Protein phosphatase 1 regulatory subunits

Locus Type

gene with protein product

Location

7q22.1

Ensembl

ENSG00000160813

Associated Conditions (1)

Progressive microcephaly

Key Variants

RS2485666331

Pathogenic

Progressive microcephaly, Progressive microcephaly

Health Risk

All Variants (1)

RSID	Category	Clinical Significance	Conditions
RS2485666331	Health Risk	Pathogenic	Progressive microcephaly, Progressive microcephaly