PPP1R1A Chromosome 12
Protein phosphatase 1 regulatory inhibitor subunit 1A
Upload your DNA to see your personal genotypes for variants in PPP1R1A.
What This Gene Does
Predicted to enable protein serine/threonine phosphatase inhibitor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
Protein phosphatase 1 regulatory subunits
Locus Type
gene with protein product
Location
12q13.2
Ensembl
ENSG00000135447
Associated Conditions (2)
Low-frequency hearing loss
Low-frequency sensorineural hearing impairment
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS202211027 | Health Risk | Conflicting classifications of pathogenicity | Low-frequency hearing loss, Low-frequency sensorineural hearing impairment, Low-frequency hearing loss |