PLCL1 Chromosome 2

Phospholipase C like 1 (inactive)
1 variant 1 Health Risk

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What This Gene Does
Predicted to enable GABA receptor binding activity and phosphatidylinositol-4,5-bisphosphate phospholipase C activity. Predicted to be involved in several processes, including gamma-aminobutyric acid signaling pathway; negative regulation of cold-induced thermogenesis; and phosphatidylinositol-mediated signaling. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"Protein phosphatase 1 regulatory subunits|C2 domain containing phospholipases"
Locus Type
gene with protein product
Location
2q33.1
Ensembl
ENSG00000115896
Key Variants
All Variants (1)
RSID Category Clinical Significance Conditions
RS142389942 Health Risk Conflicting classifications of pathogenicity
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