NCAPG2 Chromosome 7
Non-SMC condensin II complex subunit G2
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What This Gene Does
This gene encodes a protein that belongs to the Condensin2nSMC family of proteins. The encoded protein is a regulatory subunit of the condensin II complex which, along with the condensin I complex, plays a role in chromosome assembly and segregation during mitosis. A similar protein in mouse is required for early development of the embryo. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Info
Gene Group
"Condensin II subunits|Armadillo like helical domain containing"
Locus Type
gene with protein product
Location
7q36.3
Ensembl
ENSG00000146918
Associated Conditions (1)
Khan-Khan-Katsanis syndrome
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS199598836 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS1835253194 | Health Risk | Likely pathogenic | Khan-Khan-Katsanis syndrome, Khan-Khan-Katsanis syndrome |