MYBBP1A Chromosome 17
MYB binding protein 1a
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What This Gene Does
This gene encodes a nucleolar transcriptional regulator that was first identified by its ability to bind specifically to the Myb proto-oncogene protein. The encoded protein is thought to play a role in many cellular processes including response to nucleolar stress, tumor suppression and synthesis of ribosomal DNA. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Info
Gene Group
"Armadillo like helical domain containing|B-WICH chromatin-remodelling complex subunits"
Locus Type
gene with protein product
Location
17p13.2
Ensembl
ENSG00000132382
Associated Conditions (1)
Sarcoma
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS141542001 | Health Risk | Conflicting classifications of pathogenicity | Sarcoma, Sarcoma |
| RS142196126 | Health Risk | Conflicting classifications of pathogenicity | — |