MTCL1 Chromosome 18
Microtubule crosslinking factor 1
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What This Gene Does
Enables microtubule binding activity. Involved in chromosome segregation. Located in kinetochore; midbody; and spindle. [provided by Alliance of Genome Resources, Jul 2025]
Associated Conditions (2)
Inborn genetic diseases
Cerebellar ataxia
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS574852095 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS2510211807 | Health Risk | Pathogenic | Cerebellar ataxia, Cerebellar ataxia |