MOG Chromosome 6
Myelin oligodendrocyte glycoprotein
Upload your DNA to see your personal genotypes for variants in MOG.
What This Gene Does
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
"Butyrophilins|V-set domain containing"
Locus Type
gene with protein product
Location
6p22.1
Ensembl
ENSG00000204655
Associated Conditions (1)
Narcolepsy 7
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS387906655 | Health Risk | Pathogenic | Narcolepsy 7, Narcolepsy 7 |