MICAL2 Chromosome 11
Microtubule associated monooxygenase, calponin and LIM domain containing 2
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What This Gene Does
The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
Gene Info
Gene Group
"LIM domain containing|MicroRNA protein coding host genes|Bivalent Mical/EHBP Rab binding domain containing|Flavoproteins"
Locus Type
gene with protein product
Location
11p15.3
Ensembl
ENSG00000133816
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS77782413 | Health Risk | Conflicting classifications of pathogenicity | — |