MGA Chromosome 15

MAX dimerization protein MGA
1 variant 1 Health Risk

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What This Gene Does
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Part of MLL1 complex. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"MAX dimerization proteins|T-box transcription factors|MicroRNA protein coding host genes"
Locus Type
gene with protein product
Location
15q15
Ensembl
ENSG00000174197
Associated Conditions (1)
Multiple myeloma
Key Variants
All Variants (1)
RSID Category Clinical Significance Conditions
RS1595889508 Health Risk Likely pathogenic Multiple myeloma, Multiple myeloma
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