METTL4 Chromosome 18
Methyltransferase 4, N6-adenosine
Upload your DNA to see your personal genotypes for variants in METTL4.
What This Gene Does
Enables RNA methyltransferase activity and site-specific DNA-methyltransferase (adenine-specific) activity. Involved in regulation of primary metabolic process and snRNA (adenine-N6)-methylation. Located in cytosol; mitochondrial matrix; and nucleus. Part of RNA N6-methyladenosine methyltransferase complex and oxidoreductase complex. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"7BS N6-adenosine DNA/RNA methyltransferases|DNA/RNA methyltransferases"
Locus Type
gene with protein product
Location
18p11.32
Ensembl
ENSG00000101574
Associated Conditions (1)
Clear cell carcinoma of kidney
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS148311311 | Health Risk | Likely pathogenic | Clear cell carcinoma of kidney, Clear cell carcinoma of kidney |