MCTS1 Chromosome X

MCTS1 re-initiation and release factor

3 variants 3 Health Risk

Upload your DNA to see your personal genotypes for variants in MCTS1.

What This Gene Does

Enables RNA cap binding activity; ribosomal small subunit binding activity; and translation factor activity, non-nucleic acid binding. Involved in IRES-dependent viral translational initiation; cytoplasmic translational initiation; and ribosome disassembly. Is active in cytoplasm. Implicated in immunodeficiency 118. [provided by Alliance of Genome Resources, Apr 2025]

Associated Conditions (1)

Immunodeficiency 118

Key Variants

RS2521289319

Pathogenic

Immunodeficiency 118, Immunodeficiency 118

Health Risk

RS2521290553

Pathogenic

Immunodeficiency 118, Immunodeficiency 118

Health Risk

RS2521290612

Pathogenic

Immunodeficiency 118, Immunodeficiency 118

Health Risk

All Variants (3)

RSID	Category	Clinical Significance	Conditions
RS2521289319	Health Risk	Pathogenic	Immunodeficiency 118, Immunodeficiency 118
RS2521290553	Health Risk	Pathogenic	Immunodeficiency 118, Immunodeficiency 118
RS2521290612	Health Risk	Pathogenic	Immunodeficiency 118, Immunodeficiency 118