MCF2 Chromosome X
MCF.2 cell line derived transforming sequence
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What This Gene Does
The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.[provided by RefSeq, Jan 2010]
Gene Info
Gene Group
"Dbl family Rho GEFs|CRAL-TRIO lipid binding domain containing"
Locus Type
gene with protein product
Location
Xq27.1
Ensembl
ENSG00000101977
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS200810024 | Health Risk | Conflicting classifications of pathogenicity | — |