MAD2L2 Chromosome 1
Mitotic arrest deficient 2 like 2
Upload your DNA to see your personal genotypes for variants in MAD2L2.
What This Gene Does
The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
"DNA polymerases|FA complementation groups"
Locus Type
gene with protein product
Location
1p36.22
Ensembl
ENSG00000116670
Associated Conditions (1)
Fanconi anemia complementation group V
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1057517674 | Health Risk | Pathogenic | Fanconi anemia complementation group V, Fanconi anemia complementation group V |