LRRC23 Chromosome 12

Leucine rich repeat containing 23

2 variants 2 Health Risk

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What This Gene Does

Involved in flagellated sperm motility and radial spoke assembly. Located in cytoplasm and sperm flagellum. Implicated in spermatogenic failure 92. [provided by Alliance of Genome Resources, Jul 2025]

Associated Conditions (1)

Spermatogenic failure 92

Key Variants

RS1289377349

Pathogenic

Spermatogenic failure 92, Spermatogenic failure 92

Health Risk

RS1555139812

Pathogenic

Spermatogenic failure 92, Spermatogenic failure 92

Health Risk

All Variants (2)

RSID	Category	Clinical Significance	Conditions
RS1289377349	Health Risk	Pathogenic	Spermatogenic failure 92, Spermatogenic failure 92
RS1555139812	Health Risk	Pathogenic	Spermatogenic failure 92, Spermatogenic failure 92