LPAR6 Chromosome 13

Lysophosphatidic acid receptor 6
14 variants 14 Health Risk

Upload your DNA to see your personal genotypes for variants in LPAR6.

What This Gene Does
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene aligns with an internal intron of the retinoblastoma susceptibility gene in the reverse orientation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]
Gene Info
Gene Group
Lysophosphatidic acid receptors
Locus Type
gene with protein product
Location
13q14.2
Ensembl
ENSG00000139679
Associated Conditions (4)
Hypotrichosis 8
Wooly hair
autosomal recessive 1
with or without hypotrichosis
Key Variants
All Variants (14)
RSID Category Clinical Significance Conditions
RS115596308 Health Risk Conflicting classifications of pathogenicity Hypotrichosis 8, Hypotrichosis 8
RS121434306 Health Risk Likely pathogenic Hypotrichosis 8, Hypotrichosis 8
RS121434308 Health Risk Likely pathogenic Hypotrichosis 8, Hypotrichosis 8
RS1566212378 Health Risk Likely pathogenic Hypotrichosis 8, Hypotrichosis 8
RS1948803416 Health Risk Likely pathogenic Hypotrichosis 8, Hypotrichosis 8
RS2542254523 Health Risk Likely pathogenic Hypotrichosis 8, Hypotrichosis 8
RS2542255397 Health Risk Likely pathogenic Hypotrichosis 8, Hypotrichosis 8
RS2542256275 Health Risk Likely pathogenic Hypotrichosis 8, Hypotrichosis 8
RS879255262 Health Risk Likely pathogenic Hypotrichosis 8, Hypotrichosis 8
RS2138204557 Health Risk Pathogenic Hypotrichosis 8, Hypotrichosis 8
RS2542261609 Health Risk Pathogenic Hypotrichosis 8, Hypotrichosis 8
RS759807882 Health Risk Pathogenic Hypotrichosis 8, Hypotrichosis 8
RS121434307 Health Risk Pathogenic/Likely pathogenic Wooly hair, autosomal recessive 1, with or without hypotrichosis
RS121434309 Health Risk Pathogenic/Likely pathogenic Hypotrichosis 8, Hypotrichosis 8
Sign Up to Analyze Your DNA Log In